What are the causes and types of arthritis?

Arthritis means joint inflammation, but the term is used to describe around 200 conditions that affect joints, the tissues that surround the joint, and other connective tissue. It is a rheumatic condition.

The most common form of arthritis is osteoarthritis. Other common rheumatic conditions related to arthritis includeTrusted Source goutfibromyalgia, and rheumatoid arthritis (RA).

Rheumatic conditions tend to involve pain, aching, stiffness, and swelling in and around one or more joints. The symptoms can develop gradually or suddenly. Certain rheumatic conditions can also involveTrusted Source the immune system and various internal organs of the body.

Some forms of arthritis, such as rheumatoid arthritis and lupus (SLE), can affect multiple organs and cause widespread symptoms.

According to the Centers for Disease Control and Prevention (CDC), 54.4 millionTrusted Source adults in the United States have received a diagnosis of some form of arthritis. Of these, 23.7 million people have their activity curtailed in some way by their condition.

Arthritis is more common among adults aged 65 years or older, but it can affect people of all ages, including children.

Fast facts on arthritis

  • Arthritis refers to around 200 rheumatic diseases and conditions that affect joints, including lupus and rheumatoid arthritis.
  • It can cause a range of symptoms and impair a person’s ability to perform everyday tasks.
  • Physical activity has a positive effect on arthritis and can improve pain, function, and mental health.
  • Factors in the development of arthritis include injury, abnormal metabolism, genetic makeup, infections, and immune system dysfunction.
  • Treatment aims to control pain, minimize joint damage, and improve or maintain quality of life. It involves medications, physical therapies, and patient education and support.

Treatment

woman receiving physical therapy on hand
The doctor will likely recommend a course of physical therapies to help you manage some of the symptoms of arthritis.

Treatment for arthritis aims to control pain, minimize joint damage, and improve or maintain function and quality of life.

A range of medications and lifestyle strategies can help achieve this and protect joints from further damage.

Treatment might involveTrusted Source:

  • medications
  • non-pharmacologic therapies
  • physical or occupational therapy
  • splints or joint assistive aids
  • patient education and support
  • weight loss
  • surgery, including joint replacement

Medication

Non-inflammatory types of arthritis, such as osteoarthritis, are often treated with pain-reducing medications, physical activity, weight loss if the person is overweight, and self-management education.

These treatments are also applied to inflammatory types of arthritis, such as RA, along with anti-inflammatory medications such as corticosteroids and non-steroidal anti-inflammatory drugs (NSAIDs), disease-modifying anti-rheumatic drugs (DMARDs), and a relatively new class of drugs known as biologics.

Medications will depend on the type of arthritis. Commonly used drugs include:

  • Analgesics: these reduce pain, but have no effect on inflammation. Examples include acetaminophen (Tylenol), tramadol (Ultram) and narcotics containing oxycodone (Percocet, Oxycontin) or hydrocodone (Vicodin, Lortab). Tylenol is available to purchase online.
  • Non-steroidal anti-inflammatory drugs (NSAIDs): these reduce both pain and inflammation. NSAIDs include available to purchase over-the-counter or online, including ibuprofen (Advil, Motrin IB) and naproxen sodium (Aleve). Some NSAIDs are available as creams, gels or patches which can be applied to specific joints.
  • Counterirritants: some creams and ointments contain menthol or capsaicin, the ingredient that makes hot peppers spicy. Rubbing these on the skin over a painful joint can modulate pain signals from the joint and lessen pain. Various creams are available to purchase online.
  • Disease-modifying antirheumatic drugs (DMARDs): used to treat RA, DMARDs slow or stop the immune system from attacking the joints. Examples include methotrexate (Trexall) and hydroxychloroquine (Plaquenil).
  • Biologics: used with DMARDs, biologic response modifiers are genetically engineered drugs that target various protein molecules involved in the immune response. Examples include etanercept (Enbrel) and infliximab (Remicade).
  • Corticosteroids: prednisone and cortisone reduce inflammation and suppress the immune system.

To discover more evidence-based information and resources for healthy aging, visit our dedicated hub.

Natural remedies

A healthful, balanced diet with appropriate exercise, avoiding smoking, and not drinking excess alcohol can help people with arthritis maintain their overall health.

Diet

There is no specific diet that treats arthritis, but some types of food may help reduce inflammation.

The following foods, found in a Mediterranean diet, can provide many nutrients that are good for joint health:

  • fish
  • nuts and seeds
  • fruits and vegetables
  • beans
  • olive oil
  • whole grains

Foods to avoid

There are some foods that people with arthritis may want to avoid.

Nightshade vegetables, such as tomatoes, contain a chemical called solanine that some studies have linked with arthritis pain. Research findings are mixed when it comes to these vegetables, but some people have reported a reduction in arthritis symptoms when avoiding nightshade vegetables.

Self-management

Self-management of arthritis symptoms is also important.

Key strategies include:

  • staying physically active
  • achieving and maintaining a healthy weight
  • getting regular check-ups with the doctor
  • protecting joints from unnecessary stress

Seven habits that can help a person with arthritis to manage their condition are:

  1. Being organized: keep track of symptoms, pain levels, medications, and possible side effects for consultations with your doctor.
  2. Managing pain and fatigue: a medication regimen can be combined with non-medical pain management. Learning to manage fatigue is key to living comfortably with arthritis.
  3. Staying active: exercise is beneficial for managing arthritis and overall health.
  4. Balancing activity with rest: in addition to remaining active, rest is equally important when your disease is active.
  5. Eating a healthful diet: a balanced diet can help you achieve a healthy weight and control inflammation. Avoid refined, processed foods and pro-inflammatory animal-derived foods and choose whole plant foods that are high in antioxidants and that have anti-inflammatory properties.
  6. Improving sleep: poor sleep can aggravate arthritis pain and fatigue. Take steps to improve sleep hygiene so you find it easier to fall asleep and stay asleep. Avoid caffeine and strenuous exercise in the evenings and restrict screen-time just before sleeping.
  7. Caring for joints: tips for protecting joints include using the stronger, larger joints as levers when opening doors, using several joints to spread the weight of an object such as using a backpack and gripping as loosely as possible by using padded handles.

Do not sit in the same position for long periods. Take regular breaks to keep mobile.

Physical therapies

Doctors will often recommend a course of physical therapy to help patients with arthritis overcome some of the challenges and to reduce limitations on mobility.

Forms of physical therapy that may be recommended include:

  • Warm water therapy: exercises in a warm-water pool. The water supports weight and puts less pressure on the muscles and joints
  • Physical therapy: specific exercises tailored to the condition and individual needs, sometimes combined with pain-relieving treatments such as ice or hot packs and massage
  • Occupational therapy: practical advice on managing everyday tasks, choosing specialized aids and equipment, protecting the joints from further damage and managing fatigue

Physical activity

Research suggests that although individuals with arthritis may experience short-term increases in pain when first beginning exercise, continued physical activity can be an effective way to reduce symptomsTrusted Source long-term.

People with arthritis can participate in joint-friendly physical activity on their own or with friends. As many people with arthritis have another condition, such as heart disease, it is important to choose appropriate activities.

Joint-friendly physical activities that are appropriate for adults with arthritis and heart disease include:

  • walking
  • swimming
  • cycling

A health care professional can help you find ways to live a healthful lifestyle and have a better quality of life.

Natural therapies

A number of natural remedies have been suggested for different types of arthritis.

According to the organization Versus Arthritis, based in the United Kingdom (U.K.), some research has supported the use of devil’s claw, rosehip, and Boswellia, from the frankincense tree. Devil’s claw and Boswellia supplements can be purchased online.

There is some evidenceTrusted Source that turmeric may help, but more studies are needed to confirm their effectiveness.

Various other herbs and spices have been recommended for RA, but again, more research is needed. They include turmeric, garlic, ginger, black pepper, and green tea.

Many of these herbs and spices are available to purchase online in supplement form, including turmericginger, and garlic.

Anyone who is considering using natural remedies for any type of arthritis should speak to a doctor first.

Causes

There is no single cause of all types of arthritis. The cause or causes vary according to the type or form of arthritis.

Possible causes may include:

  • injury, leading to degenerative arthritis
  • abnormal metabolism, leading to gout and pseudogout
  • inheritance, such as in osteoarthritis
  • infections, such as in the arthritis of Lyme disease
  • immune system dysfunction, such as in RA and SLE

Most types of arthritis are linked to a combination of factors, but some have no obvious cause and appear to be unpredictable in their emergence.

Some people may be genetically more likely to develop certain arthritic conditions. Additional factors, such as previous injury, infection, smoking and physically demanding occupations, can interact with genes to further increase the risk of arthritis.

Diet and nutrition can play a role in managing arthritis and the risk of arthritis, although specific foods, food sensitivities or intolerances are not known to cause arthritis.

Foods that increase inflammation, particularly animal-derived foods and diets high in refined sugar, can make symptoms worse, as can eating foods that provoke an immune system response.

Gout is one type of arthritis that is closely linked to diet, as it is caused by elevated levels of uric acid which can be a result of a diet high in purines.

Diets that contain high-purine foods, such as seafood, red wine, and meats, can trigger a gout flare-up. Vegetables and other plant foods that contain high levels of purines do not appear to exacerbate gout symptoms, however.

Risk factors for arthritis

Certain risk factors have been associated with arthritis. Some of these are modifiable while others are not.

Non-modifiable arthritis risk factors:

  • Age: the risk of developing most types of arthritis increases with age.
  • Sex: most types of arthritis are more common in females, and 60 percent of all people with arthritis are female. Gout is more common in males than females.
  • Genetic factors: specific genes are associated with a higher risk of certain types of arthritis, such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and ankylosing spondylitis.

Modifiable arthritis risk factors:

  • Overweight and obesity: excess weight can contribute to both the onset and progression of knee osteoarthritis.
  • Joint injuries: damage to a joint can contribute to the development of osteoarthritis in that joint.
  • Infection: many microbial agents can infect joints and trigger the development of various forms of arthritis.
  • Occupation: certain occupations that involve repetitive knee bending and squatting are associated with osteoarthritis of the knee.

Comorbidities

More than half of adults in the U.S. with arthritis report high blood pressure. High blood pressure is associated with heart disease, the most common comorbidity among adults with arthritis.

Around 1 in 5 of adults in the U.S. who have arthritis are smokers. Smoking is associated with chronic respiratory conditions, the second most common comorbidity among adults with arthritis.MEDICAL NEWS TODAY NEWSLETTERKnowledge is power. Get our free daily newsletter.

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